Bringing Inventions to Market: Technology Transfer at Work

June 11,2025
Author
Heeya P. So
Image
Marketing Coordinator - T2 blog photo
Title
Marketing Coordinator
Center
Marshall Space Flight Center
AI SpaceFactory won NASA’s Centennial Challenge in 2019 with a 3D printed habitat structure designed for Mars. Credit: NASA

From breakthrough research to real-world application, technology transfer bridges the gap between discovery and impact. Often beginning in a lab, these innovations find their way into the hands of businesses, entrepreneurs, and everyday consumers. In this post, we'll explore how technology transfer is creating pathways for the next wave of innovation.

 

Aviation and Commercial Space

Flight updates on a black screen
The Flight Awareness Collaboration Tool (FACT) is an automation tool designed to improve airport operations during winter storms.

Innovations originally developed for military defense and space exploration — such as advanced materials, autonomous flight systems, and satellite communications — now play a crucial role in both the aviation and commercial space sectors. Composite materials for spacecraft have made modern aircraft and launch systems lighter and more fuel-efficient. Technologies like precision GPS and real-time weather monitoring, once exclusive to military applications, are now integral to commercial navigation and mission planning, ensuring safer and more efficient flights.

NASA-derived insulation technology, such as SOLIMIDE® polyimide foam, is used in the fuselage of commercial aircraft and space-bound vehicles to improve thermal and acoustic performance. Additionally, adaptive flight control systems, initially designed for planetary landers, now help optimize stability and fuel efficiency in next-gen aircraft.

As aerospace technology continues to evolve, the seamless transfer of research breakthroughs will drive innovation in air and space domains, powering emerging sectors like commercial space while optimizing safety, efficiency, and reducing costs.

AI and Machine Learning

Artificial intelligence (AI) and machine learning are reshaping industries, powering everything from automated customer service to autonomous vehicles. The successful commercialization of AI technologies has been powered by research from academic and government institutions, where breakthroughs are adapted into practical applications. For example, NASA’s AI tools developed to analyze space data have been adapted for Earth-based use, such as improving predictive analytics in industries like finance and manufacturing.

The Frontier Lab (FDL), a partnership between NASA and commercial AI firms, showcases how technology transfer accelerates AI’s impact. Since 2016, FDL has applied advanced machine learning to solve challenges in planetary defense, heliophysics, Earth science, and even medicine.

Beyond that, AI tools are helping the agricultural sector predict crop yields, optimize irrigation systems, and detect plant diseases. Through successful technology transfer, AI algorithms are customized to solve industry-specific challenges. They help businesses to not only improve efficiency but also innovate faster, automate decision-making, and scale their operations.

Cybersecurity

As cyber threats become more sophisticated, protecting digital infrastructure is essential. Innovations in encryption, data protection, biometric authentication, and threat detection systems, initially developed in research environments, are now integral to safeguarding infrastructure worldwide. Technology transfer has been crucial in making these advancements widely accessible, helping businesses and governments stay ahead of evolving threats.

For example, the NASA’s Wireless Intrusion Detection System, originally developed for secure facilities, was commercialized through technology transfer and helps businesses detect unauthorized wireless devices. AI-driven systems that were first developed for military and defense applications are now being used to monitor digital networks in real-time, quickly identifying anomalies and potential breaches.

Organizations are leveraging AI to identify vulnerabilities, reduce risks, and maintain critical security infrastructure.

Advanced Manufacturing

3D printed habitat structure designed for Mars. Credit: NASA
AI SpaceFactory won NASA’s Centennial Challenge in 2019 with a 3D printed habitat structure designed for Mars. Credit: NASA

The manufacturing industry is experiencing a major shift driven by innovations in 3D printing, robotics, and smart materials — advances made possible using NASA technology. Research in materials science and manufacturing processes, initially conducted in academic and government labs, has led to breakthroughs that improve efficiency and reduce costs.

3D printing has transformed industries like aerospace, enabling the creation of lightweight and durable custom parts that would have been too costly or complex to produce using traditional methods. Similarly, robotics and automation are streamlining production lines and reducing physical labor while enhancing precision. One example is AI SpaceFactory Inc. After 3D printing a habitat designed for Mars and working with NASA on print material made from synthetic Moon dust, the company has commercialized two separate 3D printers. This planetary construction technology is now making large-scale 3D printing more accessible on Earth.

As these technologies become more accessible, manufacturers are adopting automation to improve supply chains and reduce waste.

Biotechnology

Biotechnology continues to evolve with the commercialization of genomic research, biopharmaceuticals, and medical devices. Technology transfer has enabled companies to harness groundbreaking research to develop life saving treatments, diagnostic tools, personal medicine solutions, and improved water filtering systems.

One example is radio-frequency technology originally developed by NASA’s Jet Propulsion Laboratory for space missions — it’s being used to monitor vital signs in healthcare. Licensed to Advanced Telesensors, this technology enables contactless monitoring of heart rate and breathing. In addition, synthetic DNA used to diagnose diseases such as hepatitis and cancer was developed by Firebird Diagnostics LLC, with research funded in part by the NASA Astrobiology Program.

Whether it’s through advancements in synthetic biology or innovations in diagnostic tools, the biotechnology sector remains a leader in turning scientific discovery into practical, life-changing applications.

 

As technology evolves, the impact of successful technology transfer is clear — empowering industries to innovate, solve complex challenges, and improve lives. The future is bright for businesses that harness these advancements. To explore NASA’s breakthrough innovations, browse our patent portfolio today.

 

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