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The difference between Layered Energy Depletion Radiation Shielding (LEDRS) and Stacked Energy Depletion Radiation Shielding (SEDRS) is how the piece of matter, or shield, is analyzed as radiation passes through the matter. SEDRS involves using a defined and ordered stack of layers of shielding with different material properties such that the thickness and chemical properties of each material maximizes the absorption of energy from the radiation particles that are most damaging to the target. The SEDRS shielding method aims to provide the maximum level of energy absorption while still keeping shielding mass and volume low. The process of LEDRS involves using layers of shielding material such that the thickness of each material is designed to absorb the maximum amount of energy from the radiation particles that are most damaging to the target after subsequent layers of shielding. The more energy is absorbed by the shielding material, the less energy will be deposited in the target minimizing the required mass to achieve a resulting lower dose for a given geometrical feature. The LEDRS shielding method aims to provide the maximum level of energy absorption. The process for designing LEDRS views potential radiation shields as a cascade of effects from each shielding layer to the next and is helpful for investigating the particular effects of each layer. SEDRS and LEDRS can improve any technology that relies on the controlled manipulation of a radiation field by interaction with a material element.