Standoff Ultra-Compact Micro-Raman Sensor

The technology is a sensor for remotely detecting sub part-per-billion (ppb) levels of ambient trace gases and chemical species. The system includes a high-repetition-rate, pulsed laser module that is spectrally tuned to a desired chemical species. The photons from the laser are absorbed by the target chemical, creating an acoustic vibration that impacts a diaphragm (which acts like a speaker). A highly sensitive, photo-emf detector is then used to measure the magnitude of the vibration, which corresponds to the concentration of the target chemical. The technology is being developed for NASA's trace-gas measurement needs for validation and ground truth studies to support airborne and space-based LIDAR operations. The technology has application as a chemical sniffer to detect hazardous or toxic chemical species in the vicinity of IEDs, explosives, or other chemical agents. In such an application the sensor could detect chemical species hidden inside closed containers, bags, or car trunks.

This technology was developed to improve Armstrong's multi-patented FOSS system, which has long been used to measure temperature and liquid levels in cryogenic environments. When the sensing system's fibers trapped humidity from the surrounding environment before their submersion into cryogenic liquids, the moisture adversely affected outputs. A new manufacturing process solves this problem, increasing reliability and accuracy not only of NASA's FOSS but also any fiber optic sensing system. How It Works Armstrong has developed a two-step process to assemble the sensors. First, the bare sensor fiber is inserted into an oven to expel all moisture from the fiber coating. Then, the moisture-free fiber is placed inside a humidity-controlled glove box to prevent it from absorbing any new moisture. While inside the glove box, the fiber is inserted into a loose barrier tubing that isolates the fiber yet is still thin enough to provide adequate thermal transfer. The tubing can be further purged with various gases while it is inside the glove box to provide additional moisture isolation. This innovation is particularly useful for fiber optic systems that measure temperature and that identify any temperature stratifications within cryogenic liquids. Why It Is Better This process seals sensor fibers from environmental moisture, enabling fiber optic sensing systems to operate reliably in humid environments. The innovation eliminates erroneous readings that can occur due to moisture collection on the fiber sensors. For more information about the full portfolio of FOSS technologies, see DRC-TOPS-37 or visit https://technology-afrc.ndc.nasa.gov/featurestory/fiber-optic-sensing

Typical concentration sensors, like the one initially used in the UWMS, rely on changes in electrical conductivity to measure the concentration of a solution. These measurements using conductivity are prone to voltage drift over time, leading to unreliable measurements as the sensor ages. The optical sensor developed here uses light scattering to measure the solution concentration without the issue of voltage drift. In this sensor, light from a green LED is passed into the sensor housing where it hits a first detector (i.e., a photodiode) to establish a reference of the amount of light before scattering. Simultaneously, the light from the LED scatters through the pretreat solution and then hits a second photodiode to measure the amount of light after scattering. The difference between the amount of light measured by the two detectors is used to calculate the concentration of the pretreat solution (based upon Beer’s Law). The optical concentration sensor has been demonstrated to effectively measure pretreat concentrations in both still and flowing liquid conditions and is resistant to contamination issues as necessitated by the UWMS. The optical pretreat concentration sensor is at technology readiness level (TRL) 4 (component and/or breadboard validation in laboratory environment) and is available for patent licensing.

In order to obtain real-time temperature measurements with this technology, the phosphor can either be applied as a coating onto the surface of the object for temperature mapping, or incorporated onto a sensor and attached to the end of a fiber-optic probe for local temperature measurements. Next, the object is exposed to a pulsed light source, which causes the temperature-sensing phosphor to produce an ultra-bright broadband emission. An algorithm is used to evaluate post-pulse emission decay time, which is then converted to a precise temperature reading. State-of-the-art temperature sensing phosphors suffer from thermal quenching, or unacceptable loss of signal intensity as temperature increases. Alternative high-temperature measurement systems such as thermocouples and pyrometers, offer only spot measurements. Moreover, thermocouples suffer from attachment issues and electromagnetic interference, while pyrometers frequently suffer from reflected radiation interference and unknown surface emissivity. Cr:GdAlO3, which retains ultra-bright emission intensity to temperatures well above 1000°C, provides an ideal solution to all of these issues with a few added benefits. It has a perovskite structure that is both non-reactive and stable in high-temperature environments. Furthermore, it possesses a favorable electron energy level spacing that enables this sensor to maintain stronger signal intensity than its competitors. Due to the broad absorption and emission bands for Cr:GdAlO3 there is considerable flexibility in the choice of excitation and emission wavelength detection bands. The combination of these factors makes this technology a clear choice for luminescence-based optical high-temperature sensing for a variety of industries from aerospace to manufacturing.

This invention provides a method and system for fabricating a biomarker sensor array by dispensing one or more entities using a precisely positioned, electrically biased nanoprobe immersed in a buffered fluid over a transparent substrate. Fine patterning of the substrate can be achieved by positioning and selectively biasing the probe in a particular region, changing the pH in a sharp, localized volume of fluid less than 100 nm in diameter, resulting in a selective processing of that region. One example of the implementation of this technique is related to Dip-Pen Nanolithography (DPN), where an Atomic Force Microscope probe can be used as a pen to write protein and DNA Aptamer inks on a transparent substrate functionalized with silane-based self-assembled monolayers. But it would be recognized that the invention has a much broader range of applicability. For example, the invention can be applied to formation of patterns using biological materials, chemical materials, metals, polymers, semiconductors, small molecules, organic and inorganic thins films, or any combination of these.