Micro scale electro hydrodynamic (EHD) modular cartridge pump

Current scaffold designs and materials do not provide all of the appropriate cues necessary to mimic in-vivo conditions for tissue engineering and stem cell engineering applications. It has been hypothesized that many biomaterials, such as bone, muscle, brain and heart tissue exhibit piezoelectric and ferroelectric properties. Typical cell seeding environments incorporate biochemical cues and more recently mechanical stimuli, however, electrical cues have just recently been incorporated in standard in-vitro examinations. In order to develop their potential further, novel scaffolds are required to provide adequate cues in the in-vitro environment to direct stem cells to differentiate down controlled pathways or develop novel tissue constructs. This invention is for a scaffold that provides for such cues by mimicking the native biological environment, including biochemical, topographical, mechanical and electrical cues.

These connectors are designed to be used in harsh environments and to withstand rough handling, such as being stepped on or rolled over by wheelbarrows or light vehicles. If the demated connectors are dropped or placed on the ground, the end caps will shield them from damage and contaminants. When mated, the seal between the housings and end caps keeps contaminants out. The end caps are latched to the housings so that the caps cannot be unintentionally opened; this latch can be opened only by depressing the levers. The spring used to open or close the cap is constructed of a shape memory alloy, allowing the cap to be opened and closed an almost infinite number of times. The cap actuation levers are designed so that only a 3/4-inch pull is needed to open the cap a full 190 degrees. The housings can accept most commercial-off-the-shelf electrical or fluid connectors (including those designed for cryogenics), thus eliminating the need for specialized connectors in hostile environments. The housings can also be grounded and scaled up or down to accommodate connectors of different sizes. The housings can be constructed of steel, aluminum, composites, or even plastic, depending on the environment in which they will be used and material cost constraints.

This water filtration innovation is an acoustically driven molecular sieve embedded with small-diameter carbon nanotubes. First, water enters the device and contacts the filter matrix, which can be made of polymer, ceramic, or metallic compounds. Carbon nanotubes within the matrix allow only water molecules to pass through, leaving behind any larger molecules and contaminants. The unique aspect of the technology is its use of acoustics to help drive water through the filter. An oscillator circuit attached to the filter matrix propagates acoustic vibration, further causing water molecules to de-bond and move through the filter. This use of acoustics also eliminates dependence on gravity (and thus filter orientation) to move water through the device. When water exiting the system diminishes to a pre-determined set point, a cleaning cycle is triggered to clear the sediment from the inlet of the filter, reestablishing the standard system flow rate. Unlike other filtration systems, flushing of the filter system is not required. The combination of acoustics and small-diameter carbon nanotubes in this innovation make it an effective and efficient means of producing contaminant-free, clean water.

The CSV replaces a standard spacecraft Fill and Drain Valve to facilitate cooperative servicing. The CSV offers various advantages over standard service valves: a robotic interface, three individually actuated seals, a self-contained anti-back drive system, and built-in thermal isolation. When mounted to a spacecraft as designed, the CSV transfers all operational and induced robotic loads to the mounting structure. An anti-back drive mechanism prevents the CSV seal mechanism from inadvertent actuation. Alignment marks, thermal isolation, and a mechanical coupling capable of reacting operational and robotic loads optimize the CSV for tele-robotic operations. Unique keying of the mating interface prevents mixing of media where more than one configuration of the CSV is used. Color-coding and labels are also used to prevent operator error. The CSV has four configurations for different working fluids, all with essentially unchanged geometry and mechanics.

The Multi-Link Spherical Joint developed at NASA Johnson Space Center provides a substantial improvement over typical joints in which only two linearly actuated links move independently from one another. It was determined that the rotation point of a trussed link needed to be collocated at a shared point in space for maximum articulation. If not allowed separate rotation, the line of action through a universal joint and hinge acts effectively as another linkage. This leads to a much more complex and uncontrollable structure, especially when considering multiple dimensions. Comprising the Multi-Link Spherical Joint, a spherical shell encases the cupped ends of each six possible attachments and allows each of those attachments to be independently controlled and rotated without inhibiting the motion of the others. To do this, each link is precisely limited to 15 degrees of rotation off the link centerline, thus allowing a total of 30 degrees of rotation for each link. The shell-and-cup structure can handle the loads of linear actuators that may be used to control and vary the geometry of a truss system utilizing the new joint technology. The calculated operating load that the truss system must handle can be used to scale the size of the joint, further allowing customization of any potential truss system. Additionally, the incorporated linear actuators can be controlled and powered by wiring routed through the joint without putting undo stress on the wires during operation. Accordingly, this innovative joint technology enables more efficient deployment and precise operation of articulating structures. The Multi-Link Spherical Joint is at technology readiness level (TRL) 4 (component and/or breadboard validation in laboratory environment) and is available for patent licensing. Please note that NASA does not manufacture products itself for commercial sale.